Clean room, also known as clean room or clean room. It is the foundation of pollution control. Without clean room, pollution sensitive parts can not be mass produced. In FeD-STD-2, a dust-free room is defined as a room with air filtration, distribution, optimization, construction materials, and apparatus, in which specific, regulated operating procedures are used to control airborne particulate concentrations to achieve appropriate particulate cleanliness levels. Dust-free room refers to a specially designed room that eliminates particles, harmful air, bacteria and other pollutants in the air within a certain space range, and controls the indoor temperature, cleanliness, indoor pressure, airflow speed and airflow distribution, noise and vibration, lighting and static electricity within a certain demand range.

The differences between industrial clean rooms and biological clean rooms are shown in the table below

Comparison items: industrial clean room, biological clean room

Research Object (main)

Dust, particles only once pollution

The continuous growth and reproduction of living particles such as microorganisms and bacteria will induce secondary pollution (metabolites,)

Control methods purification measures

Mainly adopt filtering method. Coarse, medium, high three filters, coarse, medium, high, ultra-high four filters and chemical filters

Mainly to take: eradication of microbial growth conditions, control of microbial breeding, reproduction and cut off the transmission of microorganisms. Filtration and sterilization

Control objectives

Control the concentration of harmful particle size

Control the production, reproduction and spread of microorganisms, and control their metabolites

Harm to production process

Just one piece of dust in the key position can cause great harm to the product

Harmful microorganisms must reach a certain concentration before they become a hazard

Requirements for clean room building materials

All materials (wall, roof, floor, etc.) do not produce dust, dust, abrasion resistance

All materials shall be resistant to water and corrosion and shall not provide conditions for microbial breeding

Control of entry of persons and objects

People enter to change shoes, change clothes, blowing. Clean and wipe the material when entering. People and things to be separated, cleaning to be separated

People need to change shoes, change clothes, shower and sterilize; To wipe, clean and sterilize the material entering; Air feeding to filtration, sterilization, character shunt, cleaning shunt

detection

Dust particles can be detected by particle counters and displayed and printed

Microbiological detection can not measure the instantaneous value, the number of colonies can be read only after 48 hours of culture.